Translace braces into parantheses:
tr '{}' '()' < inputfile > outputfile
Translate whitespaces to tabs:
echo "This is for testing" | tr [:space:] '\t'
Squeeze repetition of characters using -s:
echo "This is for testing " | tr -s [:space:]
Delete specific characters using -d:
echo "the geek stuff" | tr -d 't'
Complement the sets using -c option:
echo "my username is 432234" | tr -cd [:digit:]
Remove non-printable characters from a file:
tr -cd [:print:] < file.txt
Join all the lines in a file into a single line:
tr -s '\n' ' ' < file.txt